Kuraridine
CAS No. : 34981-25-4
| Size | Price | Stock |
|---|---|---|
| 1mg | $425 | In-stock |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-121381 |
| M.Wt: | 438.51 |
| Formula: | C26H30O6 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Kuraridine is a prenylated flavonol extract from the roots of?Sophora flavescens. Kuraridine has an inhibitory effect on cGMP specific phosphodiesterase type 5?(PDE5) (IC50=0.64 μM)[1]. In Vitro: Kuraridine shows potent inhibitory activity (IC50=0.64 μM) against cGMP PDE5 with 2.0- and 12.9-fold selectivity over PDE3 and PDE4, respectively[1].Kuraridine induces pronounced chloride inward currents in the absence of GABA. Thecurrents does not exceed 10% of the maximal?IGABA?induced by a saturating GABA concentration (1 mM)[2].Kuraridine induces a concentration-response curves for?IGABA?enhancement (EC50=4.0±2.4 μM) in Xenopus?oocytes expressing GABAA?receptors composed of?α1, β2, and?γ2S?subunits[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Kuraridine
- Cat. No.:
- HY-121381
- Quantity:
Your information is safe with us.