Clidinium (bromide)


CAS No. : 3485-62-9

(Synonyms: Ro 2-3773)

3485-62-9
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Cat. No. : HY-B1132
M.Wt: 432.35
Formula: C22H26BrNO3
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 3485-62-9 :

Clidinium bromide is a quaternary amine antimuscarinic agent. Clidinium bromide may help symptoms of cramping and abdominal/stomach pain by decreasing stomach acid, and slowing the intestines in vivo[1]. In Vivo: Clidinium (oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days) causes constipation in mice. It leads to a significant decrease in %transit after clidinium treatment [(F(3, 28)=27.405] in mice[1].
Clidinium (oral gavage; 0.25, 0.5, and 1 mg/kg; 3 days) has a significant effect on the clonic seizure threshold induced by intravenous PTZ which received clidinium (0.25, 0.5, and 1 mg/kg) [(F(3, 35) = 14.103][1].

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