Cyclacillin
CAS No. : 3485-14-1
(Synonyms: Wy-4508; Aminocyclohexylpenicillin; Ciclacillin)
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| 10mg | $95 | In-stock |
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| Cat. No. : | HY-16158 |
| M.Wt: | 341.43 |
| Formula: | C15H23N3O4S |
| Purity: | >98 % |
| Solubility: | H2O : 16.67 mg/mL (adjust pH to 1 with 1 M HCL) |
Cyclacillin (Wy-4508) is an orally active aminopenicillin antibiotic, shows antibacterial activity against a wide range of gram-positive and gram-negative pathogens[1].
In Vitro:Cyclacillin (0-125 μg/mL) inhibits varies pathogens except Klebsiella an Enterobacter organisms with MIC values range from 0.24 μg/mL to 7.8 μg/mL[1].
In Vivo:Cyclacillin (0-287 mg/kg; p.o.; single dose) shows oral activity in mice and rescues mice injected with gram-positive and gram-negative pathogens[1].
Cyclacillin (10 mg/kg; i.v.; single dose) is absorbed by the rat intestinal tissue at relatively low concentrations (less than 1 mg/mL) followed solely Michaelis-Menten kinetics[2].
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