Metiamide
CAS No. : 34839-70-8
(Synonyms: SK&F 92058)
| Size | Price | Stock |
|---|---|---|
| 5mg | $220 | In-stock |
| 10mg | $360 | In-stock |
| 50mg | $880 | In-stock |
| 100mg | $1200 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-15540 |
| M.Wt: | 244.38 |
| Formula: | C9H16N4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 2.4 mg/mL (ultrasonic;warming);H2O : 1.67 mg/mL (ultrasonic;warming;heat to 60°C) |
Metiamide (SK&F 92058) is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide. IC50 & Target: Ki: 0.92 uM (H2 receptor) In Vitro: Metiamide (SK&F 92058) is a competitive with aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex with Ki values of 0.92 μM glycolaldehyde as the varied substrate[1]. Data is got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM)[2].
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