Polythiazide
CAS No. : 346-18-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $148 | In-stock |
| 5mg | $414 | In-stock |
| 10mg | $663 | In-stock |
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| Cat. No. : | HY-16403 |
| M.Wt: | 439.88 |
| Formula: | C11H13ClF3N3O4S3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Polythiazide is a potent and orally active thiazide diuretic agent that has antihypertensive effect. Polythiazide can decrease edema and decrease blood pressure. Polythiazide also has phototoxicity[1][2][3].
In Vitro: Polythiazide (500 μM, 1 min) induces significant phototoxic NHIK 3025 cell death under Bluelight 2000 apparatus (Ex: 325 nM)[2].
In Vivo: Polythiazide (oral gavage, 10 mg/kg, daily for 5 days) Increases plasma cholesterol levels in Cholesterol-fed C57BL/cdJ mouse[3].
Polythiazide (oral administration, 0.4 mg/kg) shows diuretic and saluretic effects in hypertensive dogs and rats[1].
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