Picamilon
CAS No. : 34562-97-5
(Synonyms: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid)
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|---|---|---|
| 5g | $54 | In-stock |
| 10g | $104 | Get quote |
| 25g | $248 | Get quote |
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| Cat. No. : | HY-107482 |
| M.Wt: | 208.22 |
| Formula: | C10H12N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C) |
Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats[1][2][3].
In Vivo:Picamilon (PM) (20 or 50 mg/kg; i.p.) significantly decreases the frequency and duration of seizure spike-wave discharges (SWDs) in Picrotoxin (HY-101391)-induced convulsive activity in rats[2].
Picamilon (250 mg/kg; p.o.) inhibits NLRP3 inflammasome activation in pancreatic cells during Alloxan (HY-W017227) -induced diabetes mellitus rats model[3].
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