Loperamide (hydrochloride)
CAS No. : 34552-83-5
(Synonyms: R-18553 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 100mg | $66 | In-stock |
| 500mg | $99 | In-stock |
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| Cat. No. : | HY-B0418A |
| M.Wt: | 513.50 |
| Formula: | C29H34Cl2N2O2 |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic);DMSO : 43.75 mg/mL (ultrasonic;warming;heat to 60°C) |
Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist[1][2][3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect[4].
In Vitro:Loperamide (17.5 µM, 1-48 h) induces hallmarks of ER stress and autophagy in GBM cells and MEFs[5].
Loperamide (17.5 µM, 48 h) decrease in LC3B and GABARAP lipidation levels in ATF4 KO cells compared to WT cells[5].
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