VUF-6884
CAS No. : 3455-10-5
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| Cat. No. : | HY-124912 |
| M.Wt: | 327.81 |
| Formula: | C18H18ClN3O |
| Purity: | >98 % |
| Solubility: |
VUF-6884 (Compound 7j) is a histamine receptor (Histamine Receptor) ligand with activity toward human H4R and H1R. Its pEC50 and pKi values against human H4R are 7.70 and 7.55, respectively, while those against human H1R are 8.17 and 8.11, respectively. VUF-6884 competitively binds to the orthosteric binding site of human H4R to displace histamine, and exhibits inverse agonist activity at human H1R[1].
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