PLGA (75:25)
CAS No. : 34346-01-5
(Synonyms: poly(lactic-co-glycolic acid) (75:25))
| Size | Price | Stock |
|---|---|---|
| 100mg | $50 | In-stock |
| 500mg | $120 | In-stock |
| 1g | $200 | In-stock |
| 5g | $440 | In-stock |
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| Cat. No. : | HY-B2247A |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides[1][2][3]. In Vitro:PLGA (75:25) (0.03-5 mg/mL; 72 h) only affects the viability of Calu-3 cells at concentrations that are too high for clinical use[1]. In Vivo:PLGA (75:25) (40 mg/kg Risperidone (PLGA (75:25) as a drug delivery carrier); s.c.; single) shows a good activity of sustained drug release for 45 days[2].
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