| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $400 | In-stock |
| 50mg | $680 | In-stock |
| 100mg | $1150 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-110399 |
| M.Wt: | 330.29 |
| Formula: | C17H14O7 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 25 mg/mL |
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand. IC50 & Target:Target: 5-lipoxygenase[1] In Vitro: In concentrations from 0.01 to 300 μM, cirsiliol causes concentration-dependent relaxation of rat isolated ileum. Cirsiliol may inhibit Ca2+ influx but stimulates Ca2+ release from intracellular stores[1]. Treatment with rhamnetin or cirsiliol reduces the proliferation of NSCLC cells through the suppression of radiation-induced Notch-1 expression[2]. In Vivo: In xenograft mouse model, tumor volume is significantly reduced by combinational treatment with irradiation and rhamnetin or cirsiliol compared with irradiation alone[2].
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