SDM25N (hydrochloride)
CAS No. : 342884-71-3
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| Cat. No. : | HY-107745 |
| M.Wt: | 450.96 |
| Formula: | C26H27ClN2O3 |
| Purity: | >98 % |
| Solubility: |
SDM25N hydrochloride, a δ-opioid receptor antagonist, is a potent DENV inhibitor. SDM25N hydrochloride targets the viral NS4B protein and restricts genomic RNA replication[1].
In Vitro:SDM25N hydrochloride (1-25 µM) shows antiviral activity against wild-type DENV2 in both Hela and BHK-21 cells, but not in the C6/36 cell line derived from the mosquito Aedes albopictus[1].
SDM25N hydrochloride restricts genomic RNA replication rather than translation of the viral genome[1].
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