(±)-Dehydroaltenusin
CAS No. : 34279-44-2
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| Cat. No. : | HY-100513 |
| M.Wt: | 288.25 |
| Formula: | C15H12O6 |
| Purity: | >98 % |
| Solubility: |
(±)-Dehydroaltenusin, an antibiotic, is a selective eukaryotic DNA polymerase α (pol α) inhibitor with an IC50 of 0.68 μM. (±)-Dehydroaltenusin can be isolated from fungus Alternaria tenuis. (±)-Dehydroaltenusin competitively inhibits the DNA template primer (Ki: 0.23 μM) and non-competitively suppresses the 2'-deoxyribonucleoside 5'-triphosphate substrate (Ki: 0.18 μM). (±)-Dehydroaltenusin induces the cancer cell S-phase cycle arrest and apoptosis. (±)-Dehydroaltenusin can be used for cancers like human adenocarcinoma research[1].
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- (±)-Dehydroaltenusin
- Cat. No.:
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