Clozapine N-oxide (Standard)


CAS No. : 34233-69-7

34233-69-7
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Cat. No. : HY-17366R
M.Wt: 342.82
Formula: C18H19ClN4O
Purity: >98 %
Solubility:
Introduction of 34233-69-7 :

Clozapine N-oxide (Standard) is the analytical standard of Clozapine N-oxide. This product is intended for research and analytical applications. Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide cannot cross the blood-brain barrier[1][2][3][4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist[5][6]. IC50 & Target:Human muscarinic designer receptors (DREADDs)[1]

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