Promegestone
CAS No. : 34184-77-5
(Synonyms: R-5020; Surgestone)
| Size | Price | Stock |
|---|---|---|
| 1mg | $650 | In-stock |
| 5mg | $1930 | In-stock |
| 10mg | $3100 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-119384 |
| M.Wt: | 326.47 |
| Formula: | C22H30O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research[1].
In Vitro: Promegestone (R-5020; 1 nM) is efficient ligand with a full agonist response profile and a low EC50 of 0.33 nM) in HELN-hPR while it only partially induced luciferase activity in U2OS-zfPR (EC50=1.93 nM)[1].
Promegestone is inactive in HELN cells that express luciferase but no functional receptor[1].
Promegestone (10 nM) robustly stimulates SLC37A2 expression in cells expressing SUMO-deficient PR, but not in cells expressing WT PR in T47D cell models[3].
In Vivo: Promegestone (R-5020; 8 mg/kg; intramuscularly)-treated pregnant mice on day 18 postbreeding has the least deterioration in extracellular collagen (lowest OD) and highest cell density compared to other groups on the day before birth[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Promegestone
- Cat. No.:
- HY-119384
- Quantity:
Your information is safe with us.