N-Acetylprocainamide (hydrochloride)
CAS No. : 34118-92-8
(Synonyms: Acecainide (hydrochloride); NAPA (hydrochloride))
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| 10mg | $77 | In-stock |
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| Cat. No. : | HY-101433 |
| M.Wt: | 313.82 |
| Formula: | C15H24ClN3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
N-Acetylprocainamide (Acecainide) hydrochloride is a class III antiarrhythmic, which blocks K+ channels. N-Acetylprocainamide hydrochloride exerts inhibitory effects on the maximum following frequency (MFF) of isolated rabbit atria. N-Acetylprocainamide hydrochloride can be used for the study of arrhythmias[1][2][3].
In Vitro:N-Acetylprocainamide (32-160 nM) hydrochloride decreases the MFF of isolated rabbit right atria in a dose-dependent manner[1].
In Vivo:N-Acetylprocainamide (30 mg/kg, i.v., over 15 min) hydrochloride restores sinus rhythm in anesthetized open-chest mongrel dogs with experimental atrial flutter induced by intercaval crush and rapid atrial pacing[3].
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