β3-AR agonist 2
CAS No. : 340757-05-3
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| Cat. No. : | HY-U00391 |
| M.Wt: | 562.68 |
| Formula: | C27H38N4O7S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
β3-AR agonist 2 is a potent and selective β3-adrenergic receptor (β3-AR) agonist with an EC50 of 8 nM. IC50 & Target: EC50: 8 nM (β3-adrenergic receptor)[1] In Vitro: β3-AR agonist 2 (Compound 26e) is found to be potent and selective at the β3 receptor, nearly completely abolishes intrinsic activity at either the β1 or β2 receptor[1]. In Vivo: β3-AR agonist 2 (Compound 26e) has significant thermogenesis effects on human β3-adrenergic receptor transgenic mice. β3-AR agonist 2 acts as a potential drug for the treatment of human obesity and type II diabetes[1].
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