Etiracetam

Etiracetam is a racetam-class nootropic agent. Etiracetam enhances learning and memory in both normal and amnesic rats. Etiracetam can be used in studies related to memory retrieval disorders and amnesic diseases such as Alzheimer's disease^[1][2]. IC50 & Target:Acetylcholine^[1]. In Vivo:Etiracetam (25-500 mg/kg; i.p.; single administration 30 min before test / 10 days) does not alter spontaneous locomotor activity or the sensitivity of healthy male Wistar rats to inescapable foot shocks, enhances learning acquisition, and inhibits avoidance behavior^[1].
Etiracetam (1-50 mg/kg; subcutaneous injection; single administration; administered 30 min before memory retention test) improves the passive avoidance performance of Wistar rats with amnesia induced by electroconvulsive shock (ECS)^[2].
Etiracetam (50 mg/kg; subcutaneous injection; daily administration; administered 30 minutes prior to daily memory retention/relearning tests on days 2-5) significantly reduces the number of maze errors and running speed, as well as decreases the error count, in amnesic SD rats during the first memory retention test^[2].