Oxaceprol
CAS No. : 33996-33-7
(Synonyms: N-Acetyl-L-hydroxyproline)
| Size | Price | Stock |
|---|---|---|
| 10g | $13 | In-stock |
| 25g | $20 | In-stock |
| 100g | $40 | In-stock |
| 500g | $155 | In-stock |
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| Cat. No. : | HY-17490 |
| M.Wt: | 173.17 |
| Formula: | C7H11NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis[1][2].
In Vivo: Oxaceprol, at 6 mg/kg/day for 7 days, significantly reduces both the surface area and wet weight of cotton pellet granulomas, being slightly less effective than indomethacin, 3 mg/kg[3].
Oxaceprol (6–54 mg/kg/day) given therapeutically had no effect on the primary paw oedema response, but inhibits secondary lesions in the ears and tail[3].
Oxaceprol does not inhibit the synthesis of prostaglandins in vitro, but markedly inhibits neutrophil infiltration into the joints of rats with adjuvant arthritis[4].
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