13(S)-HPODE
CAS No. : 33964-75-9
| Size | Price | Stock |
|---|---|---|
| 320.06 μM * 1 mL in Ethanol | $266 | Get quote |
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| Cat. No. : | HY-110406 |
| M.Wt: | 312.44 |
| Formula: | C18H32O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals. In Vitro: 13(S)-HPODE can be produced by the oxidation of linoleic acid by lipoxygenase-1 in many plants[1]. The dioxygenation catalyzed by a 15-lipoxygenase and a reduction of intermediate 13-HPODE by a glutathione-dependent peroxidase can form 13(S)-HODE[2]. 13(S)-HPODE can stimulate EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation by inhibiting the dephosphorylation of the EGFR[3].
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