TNF-α-IN-19


CAS No. : 338773-13-0

338773-13-0
Price and Availability of CAS No. : 338773-13-0
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Cat. No. : HY-114573
M.Wt: 348.71
Formula: C16H8ClF3N4
Purity: >98 %
Solubility:
Introduction of 338773-13-0 :

TNF-α-IN-19 is an inhibitor of TNFα that can block the interaction between TNFαRI, TRADD, and RIP1, the EC50 values for TNFα, IL-1β, and IL-1β/TNFα are 2.451, 3.792 and 1.54 μM, respectively. TNF-α-IN-19 only inhibits the degradation of IκBα when cells are stimulated by TNFα and not by IL-1β[1].

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