Buspirone (hydrochloride)
CAS No. : 33386-08-2
| Size | Price | Stock |
|---|---|---|
| 25mg | $25 | In-stock |
| 50mg | $42 | In-stock |
| 100mg | $66 | In-stock |
| 250mg | $132 | In-stock |
| 500mg | $185 | In-stock |
| 1g | $260 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-B1115 |
| M.Wt: | 421.96 |
| Formula: | C21H32ClN5O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research[1][2].
In Vitro: Buspirone hydrochloride (0-400 µg/mL; 6 hours) has cytotoxic effect in Lymphocytes[1].
Buspirone hydrochloride (0-180 µg/mL; 0-3 hours; Lymphocytes) induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG)[1].
In Vivo: Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) reduces anxiety/depression behaviors[2].
Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota[2].
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