NBD-556


CAS No. : 333353-44-9

333353-44-9
Price and Availability of CAS No. : 333353-44-9
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5mg $60 In-stock
10mg $100 In-stock
25mg $187 In-stock
50mg $300 In-stock
100mg $450 In-stock
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Cat. No. : HY-76648
M.Wt: 337.84
Formula: C17H24ClN3O2
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 333353-44-9 :

NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. NBD-556 shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels[1][2]. In Vitro: NBD-556 (1-100 μM) inhibits HIV-1 envelope-mediated virus-cell and cell-cell fusion[1].
NBD-556 inhibits the infection of MT-2 cells by laboratory-adapted HIV-1 IIIB, MN, and V32 strains, with IC50s of 6.5, 15.9, and 5.3 µM, respectively[1].
NBD-556 (1-100 μM) inhibits the CD4-dependent virus in a dose-dependent manner with an IC50 of 22.6 μM[1].

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