1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one
CAS No. : 332371-82-1
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| Cat. No. : | HY-N0998 |
| M.Wt: | 294.34 |
| Formula: | C19H18O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2]. In Vitro: 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 2) (1-10 µM) inhibits melanogenesis in B16 melanoma 4A5 cells with an IC50 of 1.99 µM[2].
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