DMPO
CAS No. : 3317-61-1
| Size | Price | Stock |
|---|---|---|
| 250mg | $12 | In-stock |
| 1g | $24 | In-stock |
| 5g | $110 | In-stock |
| 10g | $180 | In-stock |
| 25g | $360 | In-stock |
| 100g | $1280 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-107690 |
| M.Wt: | 113.16 |
| Formula: | C6H11NO |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
DMPO is a cell permeable hydrophillic spin trap agent for superoxide detection[1].
In Vitro: DMPO (100 μM, 24 h) attenuates SIN-1 (3-Morpholinosydnonimine (HY-126849)) (500 μM, 2 h)-mediated cytotoxicity and ROS generation in BAEC or HEK293 cells[3].
DMPO (100 μM, 24 h) increases NO levels via increasing eNOS activity and phospho-eNOS levels in BAEC cells[3].
DMPO (1-100 mM) inhibits FMLP and concanavalin A (HY-P2149) induced ·O2- secretion in neutrophils[4].
DMPO (50 mM, 24 h) inhibits Lipopolysaccharides (HY-D1056)-triggered M1-linked pro-inflammatory cytokine (IL-1β, IL-6 and TNF-α) and NO production in RAW 264,6 cells[5].
In Vivo: DMPO (10-100 mg/kg, i.p.) shows antinociceptive effect in rats subjected to Formalin induced hyperalgesia[6].
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