SU6656


CAS No. : 330161-87-0

330161-87-0
Price and Availability of CAS No. : 330161-87-0
Size Price Stock
5mg $96 In-stock
10mg $160 In-stock
25mg $320 In-stock
50mg $480 In-stock
100mg $720 In-stock
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500 mg Get quote
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Cat. No. : HY-B0789
M.Wt: 371.45
Formula: C19H21N3O3S
Purity: >98 %
Solubility: DMSO : 20 mg/mL (ultrasonic)
Introduction of 330161-87-0 :

SU6656 is a Src family kinases inhibitor with IC50s of 280, 20, 130, 170 nM for Src, Yes, Lyn, and Fyn, respectively. SU6656 inhibits FAK phosphorylation at Y576/577, Y925, Y861 sites. SU6656 also inhibits p-AKT. In Vitro: SU6656 decreases phosphorylation of Src family kinases (SFKs) in HNSCC cells[2]. In Vivo: SU6656 (2-4 mg/kg; i.p.; once) significantly decreases ischemic postconditioning (IPoCo) mediated increase in fall down time[5].

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