Tobramycin
CAS No. : 32986-56-4
(Synonyms: Nebramycin Factor 6; Deoxykanamycin B)
| Size | Price | Stock |
|---|---|---|
| 100mg | $45 | In-stock |
| 500mg | $90 | In-stock |
| 1g | $130 | In-stock |
| 5g | $260 | In-stock |
| 10g | $364 | In-stock |
| 25g | $597 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-B0441 |
| M.Wt: | 467.51 |
| Formula: | C18H37N5O9 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 100 mg/mL;DMSO : 2 mg/mL (ultrasonic) |
Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms[1].Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa[2][3].
In Vitro:Tobramycin (0-50 ng/mL; 24 hours) combinates with mycobacterium fortuitum enzyme (PodA) can greatly decreases P. aeruginosa cell viability[2].
In Vivo:Tobramycin (50-400 mg/kg/day, i.p., once every 4h) combinates with Meropenem (HY-13678) produces bacterial cell kill effect at low doses of both drugs in murine pneumonia model. [3].
Tobramycin (s.c., single dose) LD50 values in mice and rats are 441 and 969 mg/kg, respectively[4].
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