J-115814


CAS No. : 329716-61-2

329716-61-2
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Cat. No. : HY-122021
M.Wt: 572.16
Formula: C29H38ClN5O3S
Purity: >98 %
Solubility:
Introduction of 329716-61-2 :

J-115814 is a potent and selective neuropeptide Y1 antagonist with Ki values of 1.4, 1.8, 1.9, >10000, 620, 6000, >10000 nM for hY1, rY1, mY1, hY2, hY4, hY5, mY6, respectively. J-115814 inhibits feeding behaviors[1]. In Vivo:J-115814 (0.3, 1, 3, 10 mg/kg; i.v.) inhibits NPY-induced feeding in SD rats[1].
J-115814 (3, 10, 30 mg/kg; i.p.) shows anorexigenic effect in mice[1].

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