Monastrol
CAS No. : 329689-23-8
(Synonyms: (±)-Monastrol)
| Size | Price | Stock |
|---|---|---|
| 1mg | $61 | In-stock |
| 5mg | $88 | In-stock |
| 10mg | $121 | In-stock |
| 25mg | $253 | In-stock |
| 50mg | $400 | In-stock |
| 100mg | $640 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-101071A |
| M.Wt: | 292.36 |
| Formula: | C14H16N2O3S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 33 mg/mL |
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM. IC50 & Target: IC50: 14 μM (Eg5)[3] In Vitro: Monastrol is a small, cell-permeable molecule that arrests cells in mitosis by specifically inhibiting Eg5, a member of the Kinesin-5 family. Monastrol treatment of dividing cells results in spindle collapse and cell cycle arrest with a monoastral spindle, which is similar to the phenotype observed when Eg5 is inhibited by anti-Eg5 antibodies[1]. Monastrol is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cell lines. Monastrol treatment can decrease cell viability in MCF-7 tumor cells. Real-time cell growth kinetic analysis showed a decrease in the proliferation of MCF-7 cells exposed to monastrol[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Monastrol
- Cat. No.:
- HY-101071A
- Quantity:
Your information is safe with us.