L82


CAS No. : 329227-30-7

329227-30-7
Price and Availability of CAS No. : 329227-30-7
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5mg $80 In-stock
10mg $130 In-stock
25mg $240 In-stock
50mg $380 In-stock
100mg $600 In-stock
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Cat. No. : HY-15587
M.Wt: 309.67
Formula: C11H8ClN5O4
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 329227-30-7 :

L82 is a selective and uncompetitive DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM). L82 shows anti-proliferative activity to breast cancer cells[1][2]. In Vitro:L82 (0-50 μM; 6 d) shows anti-proliferative activity to breast cancer cells[2].
L82 (50 μM; 0-48 h) shows cytostatic activity due to activation of the G1/S checkpoint in MCF7 cells[2].

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