Quetiapine sulfoxide (dihydrochloride)


CAS No. : 329218-11-3

(Synonyms: Quetiapine S-oxide dihydrochloride)

329218-11-3
Price and Availability of CAS No. : 329218-11-3
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5mg $170 In-stock
10mg $270 In-stock
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Cat. No. : HY-G0014A
M.Wt: 472.43
Formula: C21H27Cl2N3O3S
Purity: >98 %
Solubility: H2O : 250 mg/mL (ultrasonic)
Introduction of 329218-11-3 :

Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2]. In Vivo: The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng?h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].

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