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|---|---|---|
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| Cat. No. : | HY-G0014 |
| M.Wt: | 399.51 |
| Formula: | C21H25N3O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2]. In Vivo: The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng?h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].
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