Quetiapine sulfoxide


CAS No. : 329216-63-9

(Synonyms: Quetiapine S-oxide)

329216-63-9
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Cat. No. : HY-G0014
M.Wt: 399.51
Formula: C21H25N3O3S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 329216-63-9 :

Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2]. In Vivo: The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng?h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing[1].

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