Cajanin
CAS No. : 32884-36-9
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| 1mg | $320 | In-stock |
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| Cat. No. : | HY-N2983 |
| M.Wt: | 300.26 |
| Formula: | C16H12O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2].
In Vitro: Cajanin shows strong mitogenic as well as differentiation-promoting effects on osteoblasts[2].
Cajanin induces the phosphorylation of both Erk1/2 and Akt[2].
In Vivo: Cajanin (10 mg/kg, p.o.; daily for 30 consecutive days) increases the BMD levels in all anatomical regions of the skeleton studied in Sprague Dawley rats[1].
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