Sulbutiamine
CAS No. : 3286-46-2
(Synonyms: Bisibuthiamine)
| Size | Price | Stock |
|---|---|---|
| 500mg | $50 | In-stock |
| 1g | $60 | In-stock |
| 5g | $108 | In-stock |
| 10g | $162 | In-stock |
| 25g | $325 | In-stock |
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| Cat. No. : | HY-B2229 |
| M.Wt: | 702.89 |
| Formula: | C32H46N8O6S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Sulbutiamine is a synthetic analogue of vitamin B1 used for the treatment of asthenia. In Vitro: Sulbutiamine shows neuroprotective effects on hippocampal CA1 pyramidal neurons subjected to oxygen-glucose deprivation. Sulbutiamine enhances electrophysiological properties such as excitatory synaptic transmissions and intrinsic neuronal membrane input resistance in a concentration-dependent manner[1]. Sulbutiamine attenuates apoptotic cell death induced by serum deprivation and stimulates GSH and GST activity in a dose dependent manner. Furthermore, sulbutiamine decreases the expression of cleaved caspase-3 and AIF[2].
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