GlyH-101
CAS No. : 328541-79-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $96 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $465 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-18336 |
| M.Wt: | 493.15 |
| Formula: | C19H15Br2N3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 58 mg/mL |
GlyH-101 is a potent CFTR inhibitor. GlyH-101 also is a potent and reversible inhibitor of the VSORC conductance. GlyH-101 shows antiproliferative activity. GlyH-101 inhibits CFTR-like current and VSORC current[1][2].
In Vitro:GlyH-101 (0-50 µM) shows antiproliferative activity in PCT and PS120 cells[1].
GlyH-101 (0.5, 1, 5, 10 µM) inhibits CFTR-like current in a concentration-dependent manner in PCT cells[1].
GlyH-101 (0.5, 1, 5, 10 µM) inhibits the VSORC current with IC50s of 5.38, 6.26 µM for PS120, PCT cells, respectively[1].
In Vivo:GlyH-101 (2.5 µg) reduces by about 80% cholera toxin-induced intestinal fluid secretion in mouse[2].
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