D-Leucine
CAS No. : 328-38-1
(Synonyms: (R)-Leucine)
| Size | Price | Stock |
|---|---|---|
| 10g | $8 | In-stock |
| 25g | $19 | In-stock |
| 100g | $49 | In-stock |
| 500g | $129 | In-stock |
| 1000g | $242 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-Y0378 |
| M.Wt: | 131.18 |
| Formula: | C6H13NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro[1]. In Vitro: In a screen of candidate neuronal receptors, D-leucine failed to compete for binding by cognate ligands, potentially suggesting a novel target. Even at low doses, D-leucine suppressed ongoing seizures at least as effectively as diazepam. These studies raise the possibility that D-leucine may represent a new class of anti-seizure agents, and that D-leucine may have a previously unknown function in eukaryotes[1].
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