N-Acetylprocainamide


CAS No. : 32795-44-1

(Synonyms: Acecainide; NAPA)

32795-44-1
Price and Availability of CAS No. : 32795-44-1
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Cat. No. : HY-B1109
M.Wt: 277.36
Formula: C15H23N3O2
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 32795-44-1 :

N-Acetylprocainamide is a class III antiarrhythmic, which blocks K+ channels. IC50 & Target: K+ channel[1] In Vitro: N-Acetylprocainamide is a K+ blocker. N-Acetylprocainamide decreases the tensions induced by K+ and methacholine. The pIC50 values for N-acetylprocainamide against the contractions induced by 0.3 and 1 μM methacholine are 2.80 ± 0.03 and 2.65 ± 0.02, respectively. And such a relaxant effect of N-Acetylprocainamide is inhibited by K+ channel blockers[1]. N-Acetylprocainamide shows no effect on Na+ absorption or Cl- secretion[2].

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