NS19504
CAS No. : 327062-46-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $58 | In-stock |
| 10mg | $100 | In-stock |
| 25mg | $220 | In-stock |
| 50mg | $380 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-110153 |
| M.Wt: | 269.16 |
| Formula: | C10H9BrN2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
NS19504 is a Ca2+-activated K+ channel (BK channel, KCa1.1 channel) activator (EC50=11.0 µM) with relaxing effect on bladder smooth muscle spontaneous phasic contractions[1]. IC50 & Target: EC50: 11.0 µM (BK channel)[1] In Vitro: NS19504 increases BK currents in freshly isolated guinea pig bladder smooth muscle cells and whole-cell. NS19504 increases the whole-cell currents response to 127 %, 194 %, 258 %, 561 % of control at a concentration of 0.32 µM, 1.0 µM, 3.2 µM and 10 µM, respectively[1].
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