PNU-292137
CAS No. : 326823-27-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $265 | In-stock |
| 10mg | $425 | In-stock |
| 25mg | $810 | In-stock |
| 50mg | $1255 | In-stock |
| 100mg | $1950 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-123045 |
| M.Wt: | 291.35 |
| Formula: | C18H17N3O |
| Purity: | >98 % |
| Solubility: |
PNU-292137 is an orally active, potent CDK2 inhibitor with IC50s of 37 nM and 92 nM for CDK2/cyclin A and CDK2/cyclin E, respectively. PNU-292137 makes interactions with the hydrophobic pocket at the back of the CDK2 ATP pocket. PNU-292137 efficiently inhibits tumor cell proliferation in human colon and prostate tumor cell lines. PNU-292137 exhibits antitumor activity (TGI>50%) in a mouse xenograft model[1].
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- Cat. No.:
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