Kaempferol 3-neohesperidoside
CAS No. : 32602-81-6
(Synonyms: Kaempferol 3-O-neohesperidoside)
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $160 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $480 | In-stock |
| 50mg | $768 | In-stock |
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| Cat. No. : | HY-107207 |
| M.Wt: | 594.52 |
| Formula: | C27H30O15 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) is a flavonoid. Kaempferol 3-neohesperidoside mimics insulin action via the PI3K/PKC pathway, significantly promoting glucose uptake and increasing muscle glycogen content in rat soleus muscles. Kaempferol 3-neohesperidoside also exhibits anti-glycation activity. Kaempferol 3-neohesperidoside binds to albumin through hydrogen bonding and hydrophobic interactions, and inhibits the formation of advanced glycation end products. Kaempferol 3-neohesperidoside can be used in studies of diabetes and its related complications[1][2]. In Vitro:Kaempferol 3-neohesperidoside (7 days) inhibits the formation of advanced glycation end products in an in vitro fructose-bovine serum albumin model, with an IC50 of 131.03 μM[1]. In Vivo:Kaempferol 3-neohesperidoside (100 mg/kg; p.o.; single dose) increases soleus muscle glycogen content by 380% in alloxan-induced diabetic rats[2].
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