GRI977143
CAS No. : 325850-81-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $95 | In-stock |
| 10mg | $165 | In-stock |
| 25mg | $345 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100676 |
| M.Wt: | 391.44 |
| Formula: | C22H17NO4S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
GRI977143 is a specific LPA2 receptor agonist, with an EC50 of 3.3 μM [1].
IC50 & Target: EC50: 3.3 μM (LPA2 receptor), 6.6 μM (LPA3 receptor)[1].
In Vitro: GRI977143 (10 μM, 24-72 h) is effective in reducing activation of caspases 3, 7, 8, and 9 and inhibits poly(ADP-ribose)polymerase 1 cleavage and DNA fragmentation in different extrinsic and intrinsic models of apoptosis[1].
GRI977143 is an effective stimulator of extracellular signal-regulated kinase 1/2 activation and promotes the assembly of a macromolecular signaling complex consisting of LPA2, Na+-H+ exchange regulatory factor 2, and thyroid receptor interacting protein 6[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- GRI977143
- Cat. No.:
- HY-100676
- Quantity:
Your information is safe with us.