CAS No. : 325465-93-8
(Synonyms: 1-Oleoyl-sn-glycero-3-phosphate (sodium); 1-Oleoyl-LPA (sodium))
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|---|---|---|
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| 10mg | $220 | In-stock |
| 25mg | $440 | In-stock |
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| Cat. No. : | HY-107614 |
| M.Wt: | 458.50 |
| Formula: | C21H40NaO7P |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic);DMSO : 1.85 mg/mL (ultrasonic;warming;adjust pH to 5 with HCl;heat to 60°C) |
1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression[1][2][3].
IC50 & Target: LPA receptor[1]
In Vitro: 1-Oleoyl lysophosphatidic acid (0.1-10 μM) sodium elicits an acute rise of [Ca2+]i in rat and rabbit osteoclasts[2].
1-Oleoyl lysophosphatidic acid (5 μM) sodium induces retraction of osteoclast lamellipodia[2].
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