Imidazoleacetic acid (hydrochloride)
CAS No. : 3251-69-2
(Synonyms: Imidazolyl-4-acetic acid (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 1g | $18 | In-stock |
| 5g | $54 | In-stock |
| 10g | $102 | In-stock |
| 25g | $229 | In-stock |
| 100g | $900 | In-stock |
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| Cat. No. : | HY-W007686 |
| M.Wt: | 162.58 |
| Formula: | C5H7ClN2O2 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic) |
Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain[1][2][3].
In Vitro: Imidazoleacetic acid (3 mM) hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM[2].
In Vivo: Imidazoleacetic acid (400 mg/kg; i.p.; single dose) hydrochloride increases the total free GABA pool size in mouse brain without a concomitant increase in the biosynthesis of GABA from glutamate[2].
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