AKTide-2T
CAS No. : 324029-01-8
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| Cat. No. : | HY-P1115 |
| M.Wt: | 1715.87 |
| Formula: | C74H114N28O20 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position[1]. In Vitro: AKTide-2T mimics the optimal phosphorylation sequence of Akt, and inhibits Akt phosphorylated Hsp27 by addition of 20 μM Akt inhibitory peptide[1].
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