Imetit (dihydrobromide)


CAS No. : 32385-58-3

(Synonyms: VUF 8325 (dihydrobromide); SKF 91105 (dihydrobromide))

32385-58-3
Price and Availability of CAS No. : 32385-58-3
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5mg $165 In-stock
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Cat. No. : HY-101173
M.Wt: 332.06
Formula: C6H12Br2N4S
Purity: >98 %
Solubility: H2O : 50 mg/mL (ultrasonic)
Introduction of 32385-58-3 :

Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM)[1][2][3]. In Vivo: Imetit dihydrobromide (2.5-10 mg/kg; i.p.) reduces the licking response induced by Apomorphine[4].

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