CAS No. : 32385-58-3
(Synonyms: VUF 8325 (dihydrobromide); SKF 91105 (dihydrobromide))
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| 5mg | $165 | In-stock |
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| Cat. No. : | HY-101173 |
| M.Wt: | 332.06 |
| Formula: | C6H12Br2N4S |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic) |
Imetit dihydrobromide (VUF 8325 dihydrobromide) is a high affinity and potent agonist of histamine H3 and H4 receptors, with Ki values of 0.3 and 2.7 nM, respectively. Imetit mimics histamine effect in triggering a shape change in eosinophils (EC50=25 nM)[1][2][3]. In Vivo: Imetit dihydrobromide (2.5-10 mg/kg; i.p.) reduces the licking response induced by Apomorphine[4].
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