Medicarpin
CAS No. : 32383-76-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $350 | In-stock |
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| Cat. No. : | HY-N3308 |
| M.Wt: | 270.28 |
| Formula: | C16H14O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of drugs[1]. In Vitro: Medicarpin (90 µM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 µM for P388 and P388/DOX cells)[1].
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