4-Hydroxyphenyl acetate
CAS No. : 3233-32-7
(Synonyms: 4-HPA; 4-Acetoxyphenol)
| Size | Price | Stock |
|---|---|---|
| 5g | $74 | In-stock |
| 10g | $107 | In-stock |
| 25g | $226 | In-stock |
| 100g | $783 | In-stock |
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| Cat. No. : | HY-30267 |
| M.Wt: | 152.15 |
| Formula: | C8H8O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
4-Hydroxyphenyl acetate (4-HPA) is a natural antioxidant and protects cells from oxidative stress-induced necrosis. 4-Hydroxyphenyl acetate blocks the increase of cellular ROS induced by oxidative stress, and up-regulates NQO1 and HO-1 genes by stabilizing and inducing the nuclear translocation of NRF2 transcription factor[1].
In Vitro: 4-Hydroxyphenyl acetate (5 μM; 24 h) protects retinal pigment epithelial (RPE) cells from oxidative stress-induced cell death[1].
4-Hydroxyphenyl acetate (5 μM; 24 h; ARPE-19 cells) inhibits the increase of ROS in response to oxidative stress and up-regulated the expression of cytoprotective genes including NQO1 and HO-1 genes[1].
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