Hexoprenaline
CAS No. : 3215-70-1
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| Cat. No. : | HY-121185 |
| M.Wt: | 420.50 |
| Formula: | C22H32N2O6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Hexoprenaline is an orally active and selective β-adrenergic receptor agonist. Hexoprenaline can dilate the bronchi. Hexoprenaline can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline exhibits anti-infection and anti-inflammmation effect. Hexoprenaline can increase placental weight and blood flow. Hexoprenaline can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds[1][2][3][4][5].
In Vitro:Hexoprenaline (10 nM-1 mM) activates adenylate cyclase in isolated rat gastric mucosal cells[2].
Hexoprenaline (10-10000 nM) increasingly stimulate 14C-Aminopyrine uptake in isolated rat gastric mucosal cells[2].
In Vivo:Hexoprenaline (sulfate) (1.5 mg/kg, s.c.) significantly reduces mortality and decreases plasma proinflammatory cytokine concentrations in mice with E. coli O157:H7-induced sepsis[4].
Hexoprenaline (0.5 mg diet, p.o., daily) increases placental weight and blood flow in blood flow[5].
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