L-SelenoMethionine


CAS No. : 3211-76-5

3211-76-5
Price and Availability of CAS No. : 3211-76-5
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1g $63 In-stock
5g $187 In-stock
25g $566 In-stock
100g $950 In-stock
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Cat. No. : HY-B1000A
M.Wt: 196.11
Formula: C5H11NO2Se
Purity: >98 %
Solubility: H2O : 14.29 mg/mL (ultrasonic);DMSO : 1 mg/mL (ultrasonic)
Introduction of 3211-76-5 :

L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase[1][2][3]. In Vitro: L-SelenoMethionine (1-500 μM; 24-72 h) is selectively inhibits the growth of prostate cancer cells, compared with normal cells[2].
L-SelenoMethionine (500 μM; 48 h) induce apoptosis in prostate cancer cells[2].
L-SelenoMethionine (500 μM; 48 h) causes an increase in arrest in the G2-M phase of the cell cycle selectively in prostate cancer cells[2].
L-SelenoMethionine (5 μM; 24 h) mitigates gene expression associated with the cellular stress response from 10 cGy irradiation[4].
In Vivo: L-SelenoMethionine (0.06-12 μg/g diet; p.o. for 3 d) partially or completely prevent the decrease in the serum or plasma levels of total antioxidants in rats exposed to gamma rays, protons or HZE particles[5].

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