Tacrine
CAS No. : 321-64-2
| Size | Price | Stock |
|---|---|---|
| 1g | $19 | In-stock |
| 5g | $68 | In-stock |
| 25g | $307 | In-stock |
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| Cat. No. : | HY-111338 |
| M.Wt: | 198.27 |
| Formula: | C13H14N2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease[1][2][3][4]. IC50 & Target:IC50: 109 nM (AChE)[3] In Vivo:Tacrine (0.3-3 mg/kg, orally, single dose) increases extracellular acetylcholine levels in rat hippocampus and improves behavioral function[1].
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