GAK inhibitor 49
CAS No. : 319492-82-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $400 | In-stock |
| 25mg | $750 | In-stock |
| 50mg | $1050 | In-stock |
| 100mg | $1450 | In-stock |
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| Cat. No. : | HY-124793 |
| M.Wt: | 370.40 |
| Formula: | C20H22N2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C) |
GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2[1]. In Vitro: GAK inhibitor 49 (compound 49) shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC50s of 28, 63 and >100 μM, respectively[1].
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